Nanotherapeutics of phytoconstituents for parasitic diseases: a short review: Nanotherapeutics of phytoconstituents for parasitic diseases: a short review

HABIBU TIJJANI; Fatima Aliyu  Mahmoud; Hafsat  Abdulkarim; Ahmed  Olatunde; Muhammad  Muhammad; Chukwuebuka  Egbuna; Mithun  Rudrapal; Kabiru Ibrahim  Karamba; Auwalu  Uba

doi:10.54117/gjpas.v1i1.2

Authors

HABIBU TIJJANI Bauchi State University Gadau
Fatima Aliyu Mahmoud Department of Biochemistry, Bauchi State University, Gadau-751105, Nigeria
Hafsat Abdulkarim Department of Biochemistry, Bauchi State University, Gadau-751105, Nigeria
Ahmed Olatunde Department of Biochemistry, Abubakar Tafawa Balewa University, Bauchi-740272, Nigeria
Muhammad Muhammad Department of Biochemistry, Bauchi State University, Gadau-751105, Nigeria
Chukwuebuka Egbuna Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Anambra State, Nigeria. Nutritional Biochemistry/Toxicology Unit, World Bank Africa Centre of Excellence, Centre for Public Health and Toxicological Research (ACE-PUTOR), University of Port-Harcourt, Rivers State, Nigeria.
Mithun Rudrapal Department of Pharmaceutical Chemistry, RMD Institute of Pharmaceutical Education and Research, Chinchwad, Pune, Maharashtra, India
Kabiru Ibrahim Karamba Department of Microbiology, Bauchi State University, Gadau.
Auwalu Uba Department of Microbiology, Bauchi State University, Gadau, Nigeria

DOI:

https://doi.org/10.54117/gjpas.v1i1.2

Keywords:

Nanotherapeutics, Phytoantioxidants, Parasite, Secondary Metabolites, Nanodelivery

Abstract

The treatment of parasitic diseases is multifaceted. The control methods require a complex interplay involving experts in public health, government policies, education, and medical sciences. Several strategies used in the treatment of parasitic diseases are considered and they are based on the availability, effectiveness, affordability, and acceptability of the used drug. Other measures include effective elimination of vector, and animal reservoirs. Interestingly, new strategies and approaches for the treatment of parasitic diseases involve nanomedical encapsulation of drugs and active compounds. Furthermore, genome, cells, and signal pathways targeting have been used for preventing and treating parasitic diseases. These approaches are used for diagnosis, and treatments of disease and to gain increased understanding of underlying disease mechanisms. Phytocompounds such as flavonoids and others are used in nanotherapeutics for treating parasitic diseases as they prevent oxidation of a liable substrate in a system, among other beneficial properties. Therefore, the present review highlights the use of several phytocompounds in nanotherapeutics to treat diseases caused by parasites.

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